Depends heavily on who’s playing the lurker (Even a moderately competent marine can solo a bald warrior and lurker with a shotgun and not much else, whilst a veteran lurker can whittle down a group of baldies into slush.)
It’s basically a roll of the dice- Backlining means an M240 or UBF is stupid strong (almost guaranteed kills if they fuck up by extinguishing while you chase), M37s are king for CQC, and M4RA is great for chasing disengaging xenos without mobility debuffs.
How effective any of this is pretty much dependent on the skill of the other guy, given the xeno player always has a huge inherent advantage.