Advanced chemline guide

Sylvia · January 22, 2026, 12:07am

This chemline guide is aimed to help both new and advanced chemists to make LOTS of pills really REALLY fast. This guide was inspired by Jennifer A.W. Kerrigan who taught me this trick. Thank you for that!

So…what’s the trick, you ask? The trick is in making maximum amount (8) of pill bottles at once. I will try to make this guide as simple as I can so even an absolute new doctor/nurse can follow it with ease.

GUIDE TO SPEEDRUN CHEMISTRY - MB, KD, IA and FE
Step A) Setup the pill machine

Insert TWO boxes of pill bottles and fill it to maximum (8x empty bottle)
Select ALL the bottles
Set the pill number to 4
Label and color accordingly (color the bottles if you are a proper chemist)

It should look like this:

STEP B) Prepare the mixes
Let’s start by the most sought after pill - IA. You will always want to make this in huge quantities as every corpsman takes this one. Set ChemMaster to 40u

IA RECIPE:
4x Nitrogen
2x Potassium
2x Silicon
2x Chlorine
4x Carbon
8x Hydrogen

RESULT: 320u Imidazoline and 160u Alkysine

STEP C) Transfer beaker to ChemMaster 3000
Create pills - now you should have 4 pills in each bottle. Repeat step B and C 3 more times
The result should look like this:

STEP D) Profit

This is the gist of the guide. You just make each chemical mix 4x and in total get 8 bottles worth of pills.

Now I will list the recipes for MB, KD and FE

MB RECIPE:
2x Sugar (30u PER CLICK!!!)
2x Oxygen (30u per CLICK!!!)
2x Water
8x Carbon

RESULT: 240u Meralyne, 240u Bicaridine and 20u leftover Inaprovaline (For the sake of speed, I recommend you leave it as it affects nothing and the amount is less than 0,5u in each pill)

KD RECIPE:
4x Carbon
4x Silicon
2x Phosphorus
2x Oxygen

RESULT: 240u Dermaline and 240u Kelotane

FE RECIPE:
12x Iron

RESULT: 480u Iron

This is my first guide, I hope I’ve not made any mistakes and it is simple enough to understand. I’ll edit it as see fit, feel free to make any recommendations about the guide so I can potentially make it clearer.

Here is showcase how fast you can be in ~8 minutes from round start:

In less than 8 minutes you can make 8x MB, KD, IA and FE each.

Thank you for reading, have a CM day!

DukeofCagliostro · January 22, 2026, 12:07am

Thank you for making this!

BasilHerb · January 22, 2026, 3:41am

dude this is actual tech holy hell

thebadperson · January 22, 2026, 5:11am

I’d seen some chem lines pumping out insane quantities really fast recently, I’m assuming this is how. Good guide.

Sylvia · January 22, 2026, 7:03pm

UPDATE - ADDITION OF MBT, KDT AND ATD

These mixtures can be done in batches of 1x, 2x or 4x instead of 8x because the total amount of chemicals required in one beaker is bigger than 250u.

MBT RECIPE:
1x Dylovene bottle from vendor
1x Inaprovaline bottle from vendor
1x Sugar (30u PER CLICK!!!)
1x Oxygen (30u PER CLICK!!!)
1x water
4x Carbon

RESULT: 120u Meralyne, 140u Bicaridine and 120u Tricordrazine
(don’t worry about the extra 20u Bicaridine, trust me, no one will notice)
1x full bottle - set to 16 pills
2x full bottle - set to 8 pills and repeat until full
4x full bottle - set to 4 pills and repeat until full

KDT RECIPE:
1x Dylovene bottle from vendor
1x Inaprovaline bottle from vendor
2x Carbon
2x Silicon
1x Phosphorus
1x Oxygen

RESULT: 120u Dermaline, 120u Kelotane and 120u Tricordrazine
1x full bottle - set to 16 pills
2x full bottle - set to 8 pills and repeat until full
4x full bottle - set to 4 pills and repeat until full

The end result will look like this:

ATD RECIPE:
3x Dylovene from vendor
1x Inaprovaline from vendor
1x Phosphorus

RESULT: 80u Dylovene, 120u Tricordrazine, 80u Arithrazine
1x full bottle - set to 16 pills
2x full bottle - set to 8 pills and repeat until full
4x full bottle - set to 4 pills and repeat until full

The end result will look like this:

These mixtures are more difficult to make however offer the advantage of tricordrazine for slightly faster healing of every damage type there is. ATD is better Dylovene.

EDIT: ADDITION OF EXOTIC MIXES: HP+, Fe + Tric, Eth (Ethylredoxrazine), NW and NWS

Short summary of each mix:
HP+ = MB and KD combined - excellent for balanced healing
Fe + Tric = Iron with added Tricordrazine - regenerates blood, provides a small bonus healing
Eth = Ethylredoxrazine - removes alcohol + HELPS AGAINST NEURO-TOXIN FROM BOILERS!
ATD with Ethyl = Better Dylovene with the added bonus of Ethyl
NW = Nitrogen, Water - counters Tramadol ODs
NWS - Nitrogen, Water, Souto - counters Tramadol and Oxycodone ODs

HP+ RECIPE:
1x Sugar (30u PER CLICK!!!)
1x Oxygen (30u PER CLICK!!!)
1x Water
6x Carbon
2x Silicon
1x Phosphorus
1x Oxygen

RESULT: 120u Meralyne, 140u Bicaridine, 120u Kelotane, 120u Dermaline
1x full bottle - set to 16 pills
2x full bottle - set to 8 pills and repeat until full
4x full bottle - set to 4 pills and repeat until full

Fe + Tric RECIPE:
2x Dylovene from vendor
2x Inaprovaline from vendor
6x Iron

RESULT: 240u Tricordrazine 240u Iron
4x full bottle - set to 8 pills and repeat until full
8x full bottle - set to 4 pills and repeat until full

ETHYLREDOXRAZINE RECIPE:
2x Dylovene from vendor
3x Oxygen
3x Carbon

RESULT: 360u of Ethylredoxrazine
6x full bottle - set to 8 pills and repeat until full

ATD (ETHYLREDOXRAZINE INCLUDED) RECIPE:
1x Oxygen
1x Sugar
1x Carbon
REMOVE 60u
2x Silicon
2x Potassium
2x Nitrogen
1x Phosphorus (20u ONLY!!)
1x Oxygen
1x Carbon

RESULT: 120u Dylovene, 120u Tricordrazine, 120u Ethylredoxrazine , 40u Arithrazine
1x full bottle - set to 16 pills
2x full bottle - set to 8 pills and repeat until full
4x full bottle - set to 4 pills and repeat until full

NOTE: Label of this bottle is tricky since 4 letters are no-go so just keep it as ATD and have it mention the added Ethyl in chem-fridge. Possible unofficial label ‘DATE’ (Dylovene, Arithrazine, Tricord, Ethyl). This way (the fastest one) makes Inaprovaline and Dylovene manually, you can by all means use vendor inaprovaline and dylovene bottles instead.

NW RECIPE:
3x Nitrogen
3x Water

RESULT: NO REACTION
6x half-full bottle - set to 8 pills

NWS RECIPE:
3x Nitrogen
3x Water
3x Lime Souto - so you have 120u

RESULT: NO REACTION
6x half-full bottle - set to 8 pills

NOTE: The odds that you’ll need more than 8 pills is extremely low, this is more than plenty. Not worth making full pill bottles, keep it only at 8 pills at most, hells, even 4 pills in a single pill bottle is a lot. However this is how I make them so feel free to experiment with the ratios and doses - to unlock your true potential as a chemist you need to experiment and try new things yourself! <3

You can never miss if you decide to make those mixtures and you’ll get bonus popularity points from corpsmen ;>

(edit #2 added exotic mixes, edit #3 adds ATD with Ethyl, edit #4 and #5 changes some wording)

DukeofCagliostro · January 22, 2026, 7:03pm

Thank you for the update. It is much appreciated!

Sylvia · January 22, 2026, 11:28pm

All this in only 5 minutes, I’ve managed to make ALL of these a minute before the first corpsman arrived to chemline. Truly insane way of making pills.

DangerRevolution · January 28, 2026, 6:49pm

Super way of making pills, holy handbook of chemistry, super guide.

darkace8708 · February 14, 2026, 1:31am

Thank you for the guide.